Anti Aging Medicine Serving Encinitas Cardiff, Carlsbad, Rancho Santa fe, Del mar, Solana beach & Other North County Coastal Cities in San Diego CA.

Telomere Leng

The main function of telomeres, which are big nucleoprotein complexes located in the extremes of the chromosomes, is to act as genomic buffers and support the erosion and reduction of DNA chromosomic ends that arise as a consequence of terminal replication. A minimal telomere length is also required in human reproduction in order to form a competent embryo.

To circumvent active DNA damage pathways that are prompted by critically short telomeres, cells must contend with the loss of telomere repeats due to various causes either by copying repeats using recombination pathways, or by synthesizing telomeric DNA “from scratch” using telomerase. The latter mechanism is found in most normal and malignant cells.